By drawing on letters, diaries and interviews, as well as Israel's rich official archives, Mr Segev mixes a meticulous narrative with a shrewd analysis of the complex Israeli psyche.The broad sequence of events is familiar.
Indeed the broad sequence diversity has limited the power of prediction and therefore the assignment of the catalytic residue.
Structural analysis in a membrane revealed that all extracellular loops of rhomboid make stabilizing interactions with substrate, but mainly through backbone interactions, explaining rhomboid's broad sequence selectivity.
A broad sequencing study has yielded hints that the culprit, called the Chikungunya virus, may recently have undergone mutations that have made it more adept at causing infections.
Owning to its excellent assay characteristics, less species requirement, broad sequence diversity and preserved intrinsic bioactivity, the proof-of-concept of MP-MB exhibits a great potential in various biomedical applications.
In addition, the mixture of cyanuric chloride and dimethylformamide is used as a new organic reagent for the conversion of a broad sequence of secondary and primary alcohols to the corresponding alkyl chlorides and iodides [23, 24].
The chronicler accounts of the encounter all vary on matters of detail, but agree on the broad sequence of events.
In particular, a loop containing the sequence GPNGF (Loop 3) accommodated broad sequence diversity and tolerated a wide range of loop lengths beyond its original 5 amino acids.
We undertook a modular approach to primer design to retrieve cooS genes from environmental sources and overcome challenges presented by the broad sequence diversity of CODH enzymes and the semi-conserved nature of the cooS primer binding sites.
Despite the broad sequence diversity represented among the different Peroxiredoxin subfamilies, the geometry of the active site region is rather conserved, with a proline residue (P40), a threonine residue (T44) and an arginine residue (R127) in van der Waals contact with the peroxidatic cysteine (C47).
