Sentence examples for broad sequence specificity and from inspiring English sources
Thus, the enzyme has a fairly broad sequence specificity and could target multiple arginine sites in histones.
- Endosomal cathepsins have broad sequence specificities and are capable of cutting proteins at many sites thereby releasing the peptides for binding by MHC molecules while simultaneously reducing the number of peptides available for MHC binding.
They display broad sequence specificity in degrading polypeptides, with a slight preference for hydrophobic residues at P1 position [ 5].
David Liu and colleagues developed a series of variant Cas9 proteins (xCas9) that have a broader sequence specificity.
Sequence specificity and surface accessibility are relatively broad criteria that can include many such non-obvious or unconventional substrates.
Bestor, T. H. & Ingram, V. M. Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA.
The result was in agreement with the earlier findings that most κB sites show no or little selectivity for a given NF-κB species and different dimers have broad sequence recognition specificities although relatively small differences in the relative affinity of NF-κB dimers for a given site can be found [ 47- 49].
However, none of the many siRNAs and shRNAs tested showed an acceptable knockdown level for silencing endogenous NBPF, which has prevented us so far from proceeding with functional studies.> -wrap-foot> Given are the target sequence, the predicted specificity (NBPF1-specific or broad NBPF specificity) and location in exons (for exon type, see ref. [ 4]) or 5'UTR.
Human carboxylesterase 1 (hCexhibitsbroadbroad substrate specificity and is involved in xenobiotic processing and endobiotic metabolism.
