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The same authors also investigated the compatible interaction with V. vinifera, which responded with a broad remodeling of the transcriptome.
In GSC animals, 1306 and 615 genes were upregulated more than fourfold and fivefold, respectively, indicating a broad remodeling of transcription.
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Considering the differentially expressed genes by functional class indicates that a broad remodelling accompanies differentiation, i.e. developmental changes are not restricted to specific protein classes or pathways.
The EGFR signaling cascade is one of the cardinal pathways regulating cell remodeling during development in a broad range of multicellular organisms [ 15].
We found that switching of chromatin remodeling mechanisms is highly correlated with a broad switch in the use of neurogenic transcription factors.
The broader vision here is to re-imagine what home remodeling in general will look like in the future.
The money will be spent on remodeling to accommodate expanded merchandise assortments and a broader merchandise mix, as well as for certain other customer service improvements.
We then used a broad-spectrum MMP inhibitor, SC080, to attempt to manipulate tissue remodeling.
However, the identified biochemical interactions with a variety of chromatin remodeling complexes and mutant analyses indicate a much broader role for GAF [ 7- 9].
These findings demonstrate interplay between chromatin remodeling complexes and histone modifications that, together, ensure robust and broad gene regulation during crucial lineage commitment decisions.
CaM Kinase II (CaMKII), a serine/threonine protein kinase with a broad spectrum of substrates, was suggested to mediate ischemic myocardial injury and adverse cardiac remodeling.
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