Sentence examples for broad regulators of from inspiring English sources

Going further, we investigated if those 17 TFs could be broad regulators of the TFs alone.

GAS6 has been proposed as a broad regulator of the innate immune response.

Finally, we discovered that RNF121 acts as a broad regulator of NF-κB signaling since its silencing also dampens NF-κB activation following stimulation of Toll-Like Receptors (TLRs), Nod-Like Receptors (NLRs), RIG-I-Like Receptors (RLRs) or after DNA damages.

Finally, in cells exposed to the DNA-damaging agent etoposide, which relies on NEMO SUMOylation and phosphorylation to convey NF-κB activity [ 16], the transcription factor activation was reduced again, suggesting that RNF121 acts as a broad regulator of NF-κB signaling.

These data strongly suggest that SMG-1 is not a broad positive regulator of the insulin pathway.

Our approach is applicable to a broader range of regulators of interest for understanding the GRNs in which they operate.

In particular the Hsp90-interacting TPR proteins have received broad attention as proposed regulators of SR function [11], [13].

The first corresponded to a broad collection of positive regulators of cell proliferation.

The signaling pathways underlying recognition of PAMPs have been studied intensively and this has led to a broad understanding of key regulators of innate immunity based on studies of cell cultures and the use of knockout rodent mutants.

MicroRNAs (miRNAs) are a new class of endogenous regulators of a broad range of physiological processes, which act by regulating gene expression post-transcriptionally.

miRNAs are emerging as critical regulators of a broad range of developmental processes [1].