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Clear determinants of a UFD-2 substrate are so far elusive; however, its involvement in cellular quality-control pathways points to a broad range of substrate proteins.
Plasmodium falciparum thymidylate kinase (PfTMPK) shows a broad range of substrate tolerance when compared to the corresponding human enzyme.
The cornea, however, is at an advantage due to the abundant expression of ALDH3A1 [41], [41] combined with the broad range of substrate specificity [42], both of these factors would likely allow for aldehyde metabolisms in the event of substantial inactivation of ALDH3A1.
Laccase and MnP both are oxidative enzyme and have broad range of substrate specificity.
A breakdown of hits by transcript class revealed a broad range of substrate specificities for the tested proteins.
This is consistent with ALDH isoforms having a broad range of substrate specificity (Koppaka et al, 2012).
Similar(48)
NQO1 is a flavoprotein that is known to catalyze two electron reduction of a broad range of substrates.
Not all microbes store fatty acids and utilize a broad range of substrates as carbon sources, and vice versa.
The new sensor construction will thus allow fast and convenient replacement of the bio-receptor and on-line assay of a broad range of substrates.
The transformation is effective for a broad range of substrates, thus enabling the expansion of constituent architectures on the heterocyclic framework.
These enzymes are responsible for catalyzing dozens chemical oxidative transformations such as hydroxylation, epoxidation, N-demethylation, etc., with very broad range of substrates [2,3].
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