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ATP-binding cassette (ABC) transporters are the largest known protein family and are mostly membrane-localized proteins that transport a broad range of substance across membranes.
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These data cover a broad range of substances and properties from many different scientific disciplines.
Like DARE, Swallow This warns against abuse of a broad range of substances, including caffeine-laden energy drinks, cigarettes, alcohol and illegal narcotics.
In addition, Tpo1p has been shown to confer yeast resistance to the herbicide barban, the plant hormone IAA, the fungicide mancozeb, and the metal cations Cd2+ and Al3+ 12, whereas Pdr5p has been implicated in the resistance to a broad range of substances such as mycotoxins19, steroid hormones20, cycloheximide21, and a vast number of antifungal compounds22.
Results show that the sensitivity of the PEC for the two drugs to the measures investigated reflects the distinct drug characteristics, suggesting that in order to ensure the successful reduction of a broad range of substances, a spectrum of measures targeting the entire lifecycle of a pharmaceutical should be implemented.
These are due to uncertainties in log P prediction that are common among different prediction implementations when considering a broad range of substances with different (and many) functional groups and ionization behaviour.
"This petition unfortunately lumps together a broad range of substances with different properties and uses without any consideration of their individual safety or benefits," added Bryan Goodman, a spokesman with the American Chemistry Council, in an email.
Pesticides are a broad range of substances most commonly used to control insects, weeds, and fungi (plant diseases).
Lipases have inherent ability to accept a broad range of substances and do not require expensive cofactors like NAD(P H.
Steroid compounds in biological samples are difficult to analyse because of the broad range of substances, the complexity of the matrices, and the low levels of detection that must be achieved.
In South Africa, a broad range of substances are abused, with alcohol being the mostly commonly abuse substance, followed by cannabis, methamphetamine and other amphetamine type stimulants, heroin, and cocaine [ 2].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com