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Consistent with the published data, embryos from females carrying any of these alleles in trans to a strong or null tube mutation exhibit a broad range of phenotypes, with a distinct phenotypic distribution for each allele.
Acute respiratory distress syndrome (ARDS) is a syndrome encompassing a broad range of phenotypes yet is often studied clinically as a single disease phenotype.
22q11.2 deletion syndrome, the most common microdeletion syndrome, exhibits a broad range of phenotypes, implying a cumbersome diagnosis due to atypical or paucisymptomatic presentations.
This will permit collaborative meta-analyses across a broad range of phenotypes.
Inbred congenic strains are powerful systems for profiling in vivo effects of genes underlying a QTL on a broad range of phenotypes [16].
The broad range of phenotypes has led to classification into clinical types including the most common severe infantile form (SMA type I), non-ambulatory variants of intermediate severity (SMA type II), and ambulatory variants (SMA types III, IV).
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Although the primary focus is on depression, a broader range of phenotypes associated with poor early caregiving environments is also considered.
Multigene panel testing allows clinicians to consider a broader range of phenotypes in a cost-effective and timely manner.
As the phenotype of the ataxin-3 overexpressing mice used in this study is mild, we were unable to assess a broader range of phenotypes.
This mouse exhibits growth retardation from postnatal day 2 onwards although it also shows a broader range of phenotypes including higher postnatal death.
Because Myc influences numerous functions, it is not surprising that myc−/− cells possess a broader range of phenotypes than Drp1 cells.
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