These pools comprised a broad range of ornithophilic and mammalophilic mosquitoes common in Germany; Culex spp. and Aedes vexans were the most abundant species.
To provide less uncertainty around model predictions, each candidate should be evaluated at a broad range of titers and against a range of mosquito parasite exposures representative of the settings a SSM-VIMT would be deployed in.
Beside a possible trans-regulation of CYP6M7, the absence of a directional selection on CYP6M7 could also stem from a more generalist functional role of this gene, particularly if it could protect the mosquito against a broad range of xenobiotics or against plant toxins (allelochemicals) or even if it were involved in functions other than detoxification.
Entomological surveys comprise a broad range of methodologies aimed at generating data on the mosquito vector and its interaction with the human host.
Quantitative transcriptome data for the malaria-transmitting mosquito Anopheles gambiae covers a broad range of biological and experimental conditions, including development, blood feeding and infection.
WNV disease will likely continue to be a public health concern for the foreseeable future; the virus has become established in a broad range of ecologic settings and is transmitted by a relatively large number of mosquito species.
This compound is particularly interesting due to its activity against a broad range of Gram-positive bacteria, as well as against fungi and mosquitoes [ 12].
This study may serve as foundation for future work by providing whole-body transcriptome data for a widespread mosquito and suggests that ALAN can affect a broad range of physiological pathways at the molecular level.
It was first identified in the mosquito Culex pipiens and has been most studied for the broad range of reproductive phenotypes that it induces in its various hosts, including cytoplasmic incompatibility, feminization, parthenogenesis, and male killing [6], [7].
Analysis was performed on the effects of larval resource management and ITNs both independently and in conjunction across a broad range of base-line human and breeding site densities (10 to 3,000 per Km2) and for mosquitoes of varying resource-searching abilities (1,000 to 3,000 m2 per day).
