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While most neurons respond to a broad range of modulation rates and to both upward and downward FM sweeps [12], [13], selectivity for the direction of FM sweeps could be found along the tonotopic gradient in the monkey auditory cortex.
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A network analyzer measures the phase and amplitude of the detected modulated electronic signal from an avalanche photodiode (APD) over a broad range of source modulation frequencies (401 points spanning ~500MHz).
This 450-kDa protein with multiple domains [ 9] has a broad range of functions, including modulation of platelet aggregation, inflammation and angiogenesis [ 10, 11].
The indazole ether core tolerated a broad range of substituents allowing for modulation of the physiochemical parameters.
Attentional rate modulation occurred for a broad range of the gAMPA gNMDA ratios, whereas attentional modulation of the gamma band activity was restricted to a relatively narrow range of gAMPA gNMDA ratios.
They exert a broad range of intracellular functions through the modulation of their subcellular localization and interacting with specific target proteins, responsible for cell growth, differentiation, motility, and cell cycle regulation [1], [2].
Peptides are competitive inhibitors of many classes of enzymes and serve a broad range of biological roles, including allosteric modulation and directing the subcellular localization of proteins.
These include a broad range of genes involved in the modulation of macrophages, Toll-response, T and B-cell proliferation and in the production of interleukin-6 and TNF-alpha, featuring an early inflammatory response that surfaces only at a later time point in WT spinal cord.
LPA modulates a broad range of cellular responses, including alterations of cell proliferation, protection against apoptosis, modulation of chemotaxis, and transcellular migration [ 5, 6], thereby affecting the survival of ovarian cancer cells, macrophages, fibroblasts, and neonatal cardiac myocytes.
The discovery that previously unidentified allosteric properties of several proteins, such as fibrinogen and myoglobin, can be triggered by anions binding, has suggested the possibility to design a new "active" role of chloride in the modulation of a broad range of biological systems.
This method can deal with a broad range of IMOPs and gives partial or complete modulation information while the existing methods give complete information for only a limited number of IMOPs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com