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However, detailed examination of 474 individual protected areas unveils a broad range of efficacy.
The strengths of this study include the randomized, placebo-controlled trial design and the broad range of efficacy and safety measures employed.
While models can be fit to a broad range of efficacy measures, this paper illustrates the advantages of using continuous outcome measures compared to binary outcome measures.
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The function of GPCRs can be modulated by a variety of ligands with a broad range of efficacies, often in a signaling pathway specific manner.
Additional advantages of combined RAF and MEK inhibition were the broader range of efficacy exhibited across melanoma cell lines and the ability to overcome vemurafenib drug resistance.
Newly designed peptides with decreased toxicity and a broader range of efficacy may have the potential to provide significant improvements in the treatment of infections.
Itraconazole has a broader range of efficacy in comparison to fluconazole, which includes Aspergillus spp. and other rare mold infections [ 18– 20].
These newly designed synthetic anti-lipopolysaccharide peptides (SALPs) with decreased toxicity and a broader range of efficacy are able to neutralize LPS-mediated effects at different degrees in vitro as well as in vivo [ 4, 7].
Thus, we compared three newly developed synthetic anti-lipopolysaccharide peptides (SALPs) with a broader range of efficacy to suppress cytokine release in plasma and CD14 mRNA expression in organ tissue in a murine, polymicrobial sepsis model.
Haloperidol, a typical antipsychotic, is non-selective and binds to a broad range of receptors, exerting efficacy mainly through the antagonism of dopamine receptors.
By exploring a broad range of immune and suicide efficacies in combination with variable degrees of population structure (from a well-mixed population to a fully structured population with no migration), simulations reveal a spectrum of evolutionary behaviors characterized by the acquisition of one, two or all three classes of defense mechanisms.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com