However, cross-sectional studies, including patients with a broad range of disease durations, seem to provide fairly reliable estimates of the course of health outcomes [ 27].
Using a broad range of gauge durations is especially important in this context, since the available evidence seems to indicate that findings of violations of CPTO may be related to the gauge durations used [ 14].
The advantage of using a broad range of gauge durations is that we can test whether the earlier observed behavioral discrepancies between short and long-time horizons [ 4, 12, 13] can be extended to the domain of procedural invariance.
The sample included 69 female subjects with a broad range of LAM duration (Table 1).
While our study enrolled only 20 patients from one center, our sample included patients of varying age, with a broad range of disease duration, and representing the full spectrum of IPF disease.
Three studies were carried out using two IL-1 isoforms (IL-1α and IL-1β) in chemically defined medium supplemented with a broad range of cytokine concentrations and durations.
This study confirmed reports of incomplete reversal of joint contractures in various animal models [ 11– 16] and improved upon previous investigations by the broad range of 18 clinically relevant durations of spontaneous recovery, from adult to geriatric age, by standardized mechanical testing, and by sufficient sample size for statistical testing.
Also, the fact that our study relates to the inclusion of a large sample of clinic patients with a broad range of disease activity, disease duration, treatment strategies, and comorbidities, rather than more homogeneous trial populations, allows insights into the routine care of RA patients.
We used a broad range of pulse frequencies and pulse durations, discharge voltage and current levels.
