The present results on horizontal activity extend prior findings of sensitization to weekly nicotine to include a broad range of doses.
Finally, predicted responses to P+K mixtures under the assumption of additive effects was modeled over a broad range of doses, and compared to experimental responses recorded in the same simple configuration.
However, a complete numerical definition of the broad range of dose and the corresponding receptor response surface, including the capture of hormetic effects in particular, is required for establishing sound quantitative and predictive cause effect relationships.
Novel orally disintegrating system based on multiparticulate form was developed, offering an alternative to encounter major issues in the design of dosage form for pediatric patients, i.e., the difficulty in swallowing large solid dosage form (tablet or capsule), and the requirement to cover a broad range of doses for different age groups.
The AHS includes individuals exposed to a broad range of doses to enhance detection of radiation effects on a variety of disease outcomes.
Results from acute and subacute toxicity tests both in mice and rats indicate safety profiles of all the test materials in a broad range of dose levels.
Results from the acute and subacute toxicity tests both in mice and rats indicated safety profiles of all test materials in a broad range of dose levels.
Unlike animal tests, which are limited by cost and resource constraints to just a few doses, in vitro assays can test chemicals at a broad range of doses that might provide better information about low-dose human effects, scientists say.
In the present study, we show that a mechanistic, systems-level computational model of the B cell transcriptional network incorporating stochastic gene expression could generate dose response curves for a broad range of doses in agreement with experimental measurements.
Analysis of the dose ratio of DA to PEG-Epo at switch indicated a broad range of dose ratios across countries, perhaps reflective of the lack of guidance in the product labels on the appropriate starting dose ratio when switching from PEG-Epo to DA.
