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Our results demonstrate that the S. cerevisiae Tpo1p and Pdr5p transporters are able to mediate resistance to a broad range of compounds of agricultural interest in yeast as well as in Arabidopsis, underscoring their potential in future biotechnological applications.
However, the most commonly used adsorbent for color removal is activated carbon [20] because of its capability for efficient adsorption of a broad range of compounds.
These are unspecific responses that might occur due to exposure to very broad range of compounds; therefore, fractionation typically results in the distribution of toxicity over many different fractions.
Laccases [E.C. 1.10.3.2] can oxidize a broad range of compounds such as phenols or amines (Keilin and Mann 1939; Bollag et al. 1988; Thurston 1994; Mikolasch and Schauer 2009) by one-electron-reactions (Nakamura 1960; Solomon et al. 2001, 2008; Munk et al. 2017).
Despite its broad range of compounds in numerous oxidation states, osmium in bulk form at ordinary temperatures and pressures resists attack by all acids and alkalis, and even aqua regia.
Protection against a broad range of compounds including carcinogens, pesticides, antitumor agents and environmental pollutants has been suggested to be mediated in part by GSTs (OMIM 138350).
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Because of this, numerous protocols for metabolite analysis have been developed to cover a broad range of compound classes, which are frequently characterized by the following workflow, as summarized in Figure 1: (i) material of choice, (ii) sample preparation and extraction, (iii) analytical methods, (iv) data processing and (v) data analysis and interpretation.
One- (1D) and two-dimensional (2D) NMR spectroscopy techniques are reliable methods for the analysis of a broad range of compound allowing the identification of compounds such as amino acids, carbohydrates, organic acids and phenolic compounds.
Importantly, our screen also revealed a broader range of compound categories that potentially enhance β-cell mass (Supplementary files 1, 2).
In accordance with several screens that have identified erg6Δ mutants with increased sensitivity to a broad range of chemical compounds, in our hands this strain was hypersensitive to the three compounds tested.
NRPS's allow synthesis of a broad range of valuable compounds, including almost all peptide-based antibiotics as well as other clinically important compounds such as immunosuppressors and anti-tumor compounds [14].
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