Sentence examples for broad phenotype of from inspiring English sources

The question remains, is the LKB1 KRAS connection part of a broad phenotype of interconnecting cancer pathways?

7 *Within the broad phenotype of behavioural variant frontotemporal dementia; clinical features in individual patients are highly variable.

This surprising finding was evaluated by Glowinski and colleagues [ 23] when they compared heritability estimates for a broad phenotype of sadness and/or anhedonia lasting 2 weeks with that of a diagnosis of MDD.

It should be noted, however, that although this idea is currently popular, it is not fully supported by behavioral data on relatives; the broad phenotype of autism does not appear to encompass the kind of nonword repetition deficits associated with CNTNAP2 and seen in individuals with SLI and their relatives (Bishop et al. 2004; Whitehouse et al. 2007).

To test whether this segregation was strictly defined by the delegate genes or represented a broader phenotype of melanoma metastases, we applied PCA to the complete data set.

Structural and functional MRI makes it possible to investigate unaffected relatives of individuals with autism to determine the neural basis of the broader phenotype of autism in terms of atypical neuroanatomy and brain function.

Athletes demonstrating echocardiographic and/or ECG abnormalities considered to represent pathological LVH were investigated further with 48 h ECG, 30 cardiopulmonary exercise test 31 32 and cardiac MRI 33 to evaluate the broader phenotype of common cardiomyopathic processes such as HCM and arrhythmogenic right ventricular cardiomyopathy, in addition to assessing the risk of SCD.

We provide 99% confidence intervals (CI) (accounting for multiple comparisons) for all these comparisons in Table 3. > -wrap-foot> To investigate whether CHD2 may be associated with the broader phenotype of GGE rather than photosensitive epilepsies specifically, we tested whether rare variants in CHD2 were enriched in patients with GGE, with or without photoparoxysmal response.

The IMPC plans to carry out a broad phenotype analysis of heterozygous adults for those mutants that are non-viable homozygotes.

These two options, as well as the inclusion of a broader phenotyping of individual patients, have great potential to elucidate etiologic factors for RLS and expand knowledge about this common disorder.

Finally, research on the broader phenotypes of ASC has found that high AQ individuals are associated with high neuroticism, low extraversion, and low agreeableness [45] or conscientiousness [46].