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The broad pattern of p53 target gene expression and apoptosis in the shh−/− mutant at 10somite stage argues against cell death due to differentiation failure, since few cells in the wild-type embryos express neuronal differentiation marker HuC at this stage [55].
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This revealed that the broad pattern of RING1B occupancy, mapping to target loci-associated CpG islands, is retained in Eed−/− mESCs.
For example, both RD29A and RD29B had low levels of H3K4me3 in a broad distribution pattern that was similar to the broad pattern of the higher levels of H3K4me3 observed during dehydration stress.
First, they show a very broad pattern of expression, including numerous tissues and organs [3], [6], [7], [8], whereas α, β and γ mRNAs expression is mainly restricted to epidermis.
The broad pattern of the results for IL6 and cortisol will require confirmation, but lack of significant changes in other cytokines was consistent across all the patients studied.
All of the PC1s showed a broad pattern of loadings across the traits (Table 2).
It is also remarkable that this convergence process is stronger throughout the second period (the real GVA per capita being the only exception).38 Overall, the broad pattern of convergence is illustrated in Fig. 2, particularly over the second period under scrutiny, thus confirming the results derived via PANIC analysis.
4E10, as previously reported [27], [41] showed an extremely broad pattern of reactivity.
Several gp120-specific and gp41-specific mAbs showed a broad pattern of reactivity with most recombinant proteins, although usually within a broad range of K50 values.
In this study the frequency, intensity, and locations of symptoms were collected to obtain a broad pattern of symptoms in line with [ 16].
Moreover, according to our initial phylogenetic analyses, the echinoderm sequences clustered with those from mammals and the epd transcript showed a broad pattern of expression in echinoderm tissues [ 12].
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