Sentence examples for broad pattern of expression from inspiring English sources
First, they show a very broad pattern of expression, including numerous tissues and organs [3], [6], [7], [8], whereas α, β and γ mRNAs expression is mainly restricted to epidermis.
The second group of embryos displayed a broad pattern of expression with the strongest signal in the middle part of the PSM (Figure 1D, n = 36/104, phase II).
We show that one unifying feature of the methylated genes in this species is their broad pattern of expression and the associated 'housekeeping' roles.
Such a mechanism is suggested by previous findings [ 11] that TICs have a broad pattern of expression across multiple samples, in contrast with other types of gene fusions that tend to have a restricted pattern of expression in particular samples.
Moreover, according to our initial phylogenetic analyses, the echinoderm sequences clustered with those from mammals and the epd transcript showed a broad pattern of expression in echinoderm tissues [ 12].
One unifying theme of the honey bee methylome is the broad pattern of expression of methylated genes indicating that gene activities required for the core cellular functions might be controlled, at least partly, by epigenetic means.
Genes with broad patterns of expression, probably those that have housekeeping functions, were preferentially conserved, while more specialized genes were often lost [11].
Given that only a few RBR genes have broad patterns of expression and have strong effects on fitness, it is possible that, under the right circumstances (e. g. modifications of the functions of cell types or tissues, changes in the proteins to be ubiquitinated, etc), the rest may be lost without much trouble [11].
Notable exceptions to this pattern are the Class II KNOX genes, which tend to have broad patterns of expression [ 52], and MADS-box transcription factors, which regulate diverse developmental processes [ 53].
In order to assess whether the correlation between our predictions and changes in metabolite concentration was due to these broad patterns of expression changes versus the modulation of specific genes, we performed a permutation analysis designed to assess the specificity of our results (Fig. 1b).
