Therefore, in this study we present for the first time systematic expression patterns of ITIH genes in a broad panel of human normal and tumor tissue samples.
In the present paper, we performed an immunohistochemical study using tissue microarrays (TMA) containing a broad panel of human normal tissues (Tissue Array Network, Rockville, MD, USA), in search for possible human cell-type-specific expression of HSPA2 and HSPA1 proteins.
Oncomine centralizes expression profiles of over 3762 microarray experiments covering a broad panel of human cancers and normal tissues and can be used to link expression of novel genes with different grades of tumors, tumor sub-types and, as has been recently shown for CD200 [94].
It is particularly interesting that there is no reactivity in various normal human cells, including distinct classes of lymphocyte subpopulations and neutrophils, as well as a broad panel of human organs.
The specificity of E8 scFv was assessed by flow cytometry on a broad panel of human cells and BOSC23 cells, ectopically expressing members of the CEACAM protein family, and by immunohistochemical staining of tumor and normal human tissues.
We included a broad panel of organisms using conventional and novel quantitative PCR diagnostics.
In summary, reovirus is potently oncolytic in a broad panel of SCCHN cell lines.
No unspecific staining was observed on a broad panel of human organs (Table 4, Figure 9).
We found that SH potently inhibited cell viability of a broad panel of breast cancer cell lines.
The broad panel of cell-specific antibodies focused on B, T lymphocytes (Tregs, Th17, NKT), NK cells, monocytes and neutrophils.
