What is most striking about the data from agitation, depression, apathy, and psychosis in AD is the broad overlap of regions associated with each NPS syndrome, particularly regions known to be associated with the salience network (anterior cingulate and insula), mood regulation (amygdala), and motivated behavior (frontal cortex).
Diploids, tetraploids and hexaploids were altitudinally segregated, but with broad overlap.
These sets were overlapped with the group of 351 NP-responsive genes to produce four subsets of 141 (Abr), 114 (Pst), 34 (NaC), and 16 (Drou) differentially-expressed genes, with broad overlap between the Abr- and Pst-responsive subsets.
Common to most of these subsyndromes is the broad overlap of regions associated with the salience network (anterior cingulate and insula), mood regulation (amygdala), and motivated behavior (frontal cortex).
Given the broad overlap of CpG islands with gene promoters and other regulatory features, this may be a means to highlight regulatory regions in large and complex vertebrate genomes.
The values used for the correlation analyses showed a continuous distribution with a relatively broad overlap between the three samples rather then group-centred clusters.
These observations as well as the CTX-II data were recently confirmed [ 17], although there was again broad overlap in biomarker levels of patients with and without progression of joint damage.
For an amorphous materials like coal, the graphitic band (G-band) and defect band (D-band) are broad and overlap with each other.
Primarily, lines with delayed courtship and/or chaining behavior tended to have broad CNS overlap with FruM.
In ADHD, a disease with high comorbidity and a broad symptom overlap with mania [ 21, 22], psychostimulants effectively reduce attention deficits, sensation seeking behaviour and hyperactivity, symptoms which are also present in mania [ 23, 24].
