Sentence examples for broad modification in from inspiring English sources

The Justice Department praised the decision to block the law for 2012 and welcomed "the court's agreement that South Carolina's law required broad modification in order to respond to the serious concerns raised by the attorney general that the law as written would exclude minority voters".

We establish the transcriptional relevance of a difference in an H3K9me3+ broad modification in that it affected transcription of CACNG7.

We operationally define a peak as a broad modification if it is >50 kb in extent.

In this region, we found a broad modification (H3K9me3+) in B73 cells but not in B12 cells.

We detected differences among cell types in broad modification regions for H3K27me3 in many of the more lengthy regions that were tiled in this array format.

We verified that a change in a broad modification affected gene expression of CACNG7.

We operationally defined a broad modification as >50 kb in length.

(4) We detected significant and clear changes in broad modification areas for H3K27me3 and, to a lesser extent, for H3K9me3, implying that the processes creating or maintaining these broad modifications differed in activity among cell types; in one case we verified that this change in a broad modification affected gene expression.

We use the term "broad modification" to denote long regions of chromosomal space in which there is a given epigenetic modification present continuously (>50 kb), as opposed to focal regions of modification ("peaks") in a promoter or other region.

This broad modification was restricted to H3K9me3 and was not present with H3K27me3 in this region.

These broad modifications are prevalent in the human genome [ 16].