Sentence examples for broad induction of from inspiring English sources

In vivo, systemic administration of lipopolysaccharide (LPS) resulted in a broad induction of cytokines and chemokines in plasma that was significantly attenuated in EP2-deficient mice.

We observed a broad induction of ephrins and ephrin receptors in only a single hMSC population (batch 4), where ephrins A1 and B3 and ephrin receptors B1, A4 and A3 were induced by SYT-SSX1.

With respect to the oncogenic response arm, Myc activation results in a broad induction of both the transcriptional (RNAPII) and protein translation machineries.

Broad induction of GADD45-β and -γ could contribute to increased survival of immune cells through interaction with NF-κB pathway [ 20, 21].

These changes are accompanied by a broad induction of stress-responsive genes that may help the AtUCP1-overexpressing cells reduce the levels of ROS and perform better under stress conditions.

Thus, a broad induction of a mucin-producing cell secretory program, characteristic of epithelial malignancies, may represent an early molecular phenotype relevant to smoking-induced carcinogenesis in the distal airways.

The broader induction of cell proliferation associated with Mst1/Mst2 inactivation appears to indicate that multiple cell lineages may undergo transformation in this context.

Broad induction at weaning inhibited proliferation of intestinal transit-amplifying and Lgr5+ stem cells and rapidly imposed features of aging, including hair loss, skin wrinkling, reduced body weight and subcutaneous fat, an increased myeloid fraction in peripheral blood, poor dentition, and cataracts.

Induction of broad HIV-1 neutralizing antibodies should be a major goal of an effective HIV-1 vaccine.

An efficient vaccine against HCV infection requires induction of broad cellular and humoral immune responses against several viral proteins.

We conclude that induction of broad immunity is likely to require immunogen sequences that encompass multiple variants.