Sentence examples for broad groups of genes from inspiring English sources
The protein kinase complement (defined as "kinome") represents a significant fraction of the human genome, and recently Manning et al. organized it into a dendogram containing nine broad groups of genes [5].
The analytic framework identified three broad groups of genes from a joint analyses of in vitro and in vivo rats toxicogenomic experiments.
The protein kinase complement (defined as 'kinome') represents a significant fraction of the human genome, and recently Manning et al. [ 11] organised it into a dendogram containing nine broad groups of genes.
This term covers a broad group of genes primarily involved in cell signalling and includes a number of cytokines.
This is an appealing concept as it links propensity for increased genetic diversity with subtle functional differences in a class of proteins that can amplify these genetic influences because they impact the transcriptional regulation of a much broader group of genes.
Further downstream, NF-κB-dependent processes in RASFs include the transcription of a broad group of target genes, comprising transcription factors such as Ets and ESE, antiapoptotic genes such as BIRC-3, and the FLIP-like gene GG2-1, as well as pro-inflammatory cytokines and effector molecules such as COXs, which catalyze the formation of prostaglandins.
We selected a broad group of candidate genes in the DNA repair and response pathways (Table S1) that likely interact with BRCA1 or BRCA2 or are involved in double strand break, mismatch repair, nucleotide excision repair, or base excision repair.
Four broad groups of quality indicators in gene expression profiling studies (clinical, tissue, RNA, and microarray quality) were identified.
Outside of the three broad groups of proteins detailed above are a large number of genes that may modify the outcome of a systemic inflammatory insult.
