Exact(1)
To the extent that tissues overlap between blots, mouse Neat1 and Neat2/Malat-1 similarlylarly broad expression to human NEAT1 and NEAT2/MALAT-1, withighestst levels in ovary, kidney, lung and thymus.
Similar(59)
This is consistent with its proposed function to restrict proneural gene activity from broad expression domains to single neural progenitors.
Though 293T cells efficiently express genes from CMV promoter-driven vectors, there is a need to identify other cells that exhibit broader expression properties to express proteins that may not be expressed in 293T cells.
In contrast to this broad expression pattern, AtMDL3 expression seems to be restricted to cotyledons, rosette leaves and sepals (i.e. all types of green leaves; Additional file 2: Figure S2A and Additional file 3: Table S1).
For example, genes with high expression intensities or broad expression patterns tend to evolve slowly [ 30- 37] so it is not clear with which degree each variable influences duplicate gene persistence after factoring out the role of the other.
The actual numbers of neurons with Gal4 expression were not quantified because this preselection screen was conducted primarily to exclude lines with broad expression patterns and thus to facilitate the later identification of neurons whose activation correlated with induced behaviors.
Due to the broad expression pattern of RIα, this approach to selectively inhibit PKA activity using the Cre/loxP system should prove useful for the study of PKA signaling in many different cellular and physiological responses in vivo.
When exon 5 was disrupted in the terminally tagged reporter fusion, to block expression arising from transcripts a and b, broad expression of GFP continued to be observed, but with the nuclear localization lost (WBID Expr9831).
In gain-of-function experiments, DMB positioning is sensitive to Engrailed paracrine activity, although one-cell stage Engrailed mRNA injection should lead to the broad expression of Engrailed, including in cells that respond to extracellular Engrailed.
In fact, troglitazone, as all thiazolidinediones, has a wide systemic distribution due to broad expression of PPARγ.
As stated above in the introduction, controversial reports exist regarding the expression of LRP1b in human tissues ranging from restricted [4] to broad expression [2,5].
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