The financial crisis that began in August 2007 has been the most severe of the post-World War II era and, very possibly once one takes into account the global scope of the crisis, its broad effects on a range of markets and institutions, and the number of systemically critical financial institutions that failed or came close to failure the worst in modern history.
"The types of healthy bacteria in the gut differ in babies born by caesarean and vaginal delivery, which can have broad effects on health," he said.
The F.C.C.'s decision, which probably will not be final for about a year, will have broad effects on consumers and companies.
Similarly, in rodent and primate trials, antidepressants have broad effects on both healthy animals and animals with conditions that resemble mood disruptions in humans.
It appears to me that it would have very broad effects at the global level on many things and it would have very broad effects on bilateral issues and issues on the Latin American agenda.
Natural melanocortin peptides exert broad effects on the host and they have remarkable therapeutic potential.
Moreover, for drugs that may not need to enter into cells or drugs that have broad effects on multiple cell types, enriched tissue concentrations could be beneficial.
We need to be cautious with microbiome manipulation interventions on their broad effects on the host beyond the conditions they are designed to treat.
Since its discovery, our understanding of leptin's biological functions has expanded from antiobesity to broad effects on reproduction, hematopoiesis, angiogenesis, blood pressure, bone mass, lymphoid organ homeostasis, and T lymphocyte systems.
