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However, detection of small nutrients is challenging, considering the high diversity and broad dynamic range of molecules in food samples.
Small nutrients detection is challenging due to the high diversity and broad dynamic range of molecules in food samples, and a further issue is to track low abundance toxins.
There are many challenges for the study of proteins in biological systems, including a broad dynamic range of expression, heterogeneity, complexity of modifications and many technical and preparatory steps prone to the introduction of bias.
Here, we demonstrate computationally how two classic genetic oscillators, the dual-feedback oscillator and the repressilator, can be re-designed to provide independent control of amplitude and period and improve tunability that is, a broad dynamic range of periods and amplitudes accessible through the input "dials".
A broad dynamic range of standards was used to account for the varied expression levels of different targeted genes.
The generic model exhibited the dramatic amplification and broad dynamic range of gradient-sensing in wild-type cells, as well as defective polarization for "mutant" parameter values.
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With broad dynamic ranges of three to four logs for each kit, determination is enabled from 1 ng/ml up to 1 mg/ml IgG concentrations.
In preparative protein chromatography, broad dynamic ranges of protein concentrations as well as co-elution of product and impurities are common.
The use of iTRAQ has become a consolidated technique in quantitative proteomics since large fold changes of protein expression within broad dynamic ranges of protein abundance can be measured quite accurately [ 39].
As previously established in other studies, the absolute magnitudes of normalized signals reflects the broader dynamic range of the qPCR method compared to microarray measurements [ 53, 64].
However, other neurons within or outside the cortical column (e.g. in the colliculus; Cohen & Castro-Alamancos, 2010) may show a broader dynamic range of firing output at larger stimulus intensities.
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