On one hand, our ability to differentiate one's broad mood disorder status from healthy controls points to detection of potential transdiagnostic characteristics, enhancing the generalizability of results.
We report parametric (GH, Genehunter) and allele-sharing linkage (Aspex) results using a broad spectrum disorder case definition.
A computerised predictive algorithm generates "unlikely", "possible" or "probable" ratings for four broad categories of disorders, namely conduct disorder, emotional disorder, hyperactivity disorder, and any psychiatric disorder.
Instead, the new manual will have a broader learning disorder category to cover several conditions including dyslexia, which causes difficulty understanding letters and recognising written words.
In conclusion, our study showed that intranasal insulin provided strong neuroprotection in the 6-OHDA rat PD model, suggesting that insulin signaling may be a novel therapeutic target in broad neurodegenerative disorders.
Prosecutor Louis Bouthillier argued that Magnotta probably suffers from a broader personality disorder such as narcissistic personality, which would mean that at the time of the murder, he was more than capable of understanding his actions.
In addition to these broad biogenic disorders, there are additional single-enzyme peroxisome diseases that share many of the same traits as these more serious disorders.
In the case of screening for Pompe disease, however, the focus on childhood disorders would be loosened as Pompe disease is a broad-phenotype disorder and symptoms may present at any age, including in adulthood.
Because of heightened interest in PTSD and anxiety disorders in general in military samples, separate analyses were performed to identify predictors of PTSD specifically, and the broader anxiety disorder category (which subsumes PTSD).
Based on both symptoms and the corresponding impact reported by parents, teachers and self-report, predictive algorithms have been developed for a broad category, 'any disorder', as well as for three subcategories: conduct disorders, hyperactivity disorders, and emotional disorders.
The aim is to increase transparency and stimulate informed policy-making in expanding neonatal screening, especially of broad-phenotype disorders.
