This background expression of Venus did not differ significantly between cell types of the peripheral blood (Fig. 4) making broad differences in lacI expression across the different haematopoietic cell types analyzed unlikely.
Surprisingly, broad differences in gene expression patterns were observed.
These included transcripts that encode various elastases, cathepsins, proteases and immune function transcripts, suggesting that rainbow trout are exhibiting broad differences in transcriptome expression between the sexes throughout life.
An initial analysis comparing animals with rejection (allograft recipients; BN rats) to those without rejection (isograft recipients; DA rats) indicated broad differences in gene expression and the possibility of multiple, strong biomarkers that could distinguish these phenotypes.
Obviously, there are broad differences in CYP450 gene expression between hESC-derived hepatocyte-like cells generated in different studies.
Differences in replication timing could be a consequence of local or broad differences in chromatin structure.
CK1δ expression profiling in the brain indicated a broad distribution of CK1δ but differences in expression levels and subcellular localisation were detected.
To further dissect these relationships, we established a panel of 21 recombinant inbred lines that showed a broad range of aggregation phenotypes, independent of differences in expression levels.
At 5 and 15 DAI, i.e., once nematode infection had progressed, root samples clustered predominantly in accordance with mj-far-1 overexpression, revealing broad, global differences in the expression levels of DEGs between OE and Kan root lines.
