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There was no evidence of heterogeneity among study centres, except for the association between ED and ΔWCBMI in women (P for heterogeneity = 0.035), driven by a single centre (Doetinchem, the Netherlands) with a small sample size and broad confidence interval, that deviated from the other centres.
Although this resembles many acceptable forms of medical intervention, including URTI preventive measures such as influenza vaccination, the broad confidence interval indicates uncertainty surrounding our results.
The strongest reported association was with assisted transfer compared to self-transfer; however, this had a very broad confidence interval: OR 29.7 (95% CI 3.6-242) [ 46].
This also applies to the gender stratified estimations: in women a RR of 2.17 was calculated with a fairly broad confidence interval (95 % CI: 1.48 3.18).
The highest estimate (yet with a rather broad confidence interval) was found in the Pihlajavesi area and the lowest in Northern Saimaa.
The association with funding source reached statistical significance, but with a broad confidence interval with the trend favouring privately-funded patients.
Similar(47)
Six grams per day oral ganciclovir was most similar in efficacy to IV, although broad confidence intervals prevented a conclusive comparison.
We found that most studies included a sufficient number of patients and controls and reported mean PPT values with broad confidence intervals.
Nevertheless, the identification of such complex moderations is often subject to high standard errors and broad confidence intervals (Afshartous and Preston 2011).
The European clinic studies included 100 person with episodic and chronic migraine, respectively, while the American clinic study included 72 persons with episodic migraine and 128 persons with chronic migraine, providing relative broad confidence intervals for the EDS prevalence, i.e. 14% (8 22%), 20% (13 29%), 32% (25 48%) and 40% (31 49%).
These numbers seem to be more realistic when compared to the observed values in other higher plants, especially considering broad confidence intervals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com