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This is important, for example, where a very broad concentration range is required for systems with different KM values.
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The effects of these products at a broad concentration range were tested on Escherichia coli KO11, a strain engineered for cellulosic ethanol production.
In real-time PCR phage quantification (qPhage), reproducible quantification was attained over a broad concentration range and was linear over at least eight orders of magnitude, far better than with the conventional approach and also much more sensitive than real-time PCR phage quantification reports [25] [26].
Although CGP-37157 and flunarizine were determined partially active, in a relative broad concentration range, calmidazolium was determined far more potent (∼3 fold) inhibitor in DRG cultures enriched in nociceptive neurons with TRPV1 immunoreactivity (data not shown) (Fig. 6).
The characteristics of cell death were investigated after exposure of CCRF-CEM.f2 cells to five drugs over a broad concentration range; these were the glucocorticoid dexamethasone (DXM), the mitotic inhibitor vincristine (VIN) and three antimetabolites, methotrexate (MTX), 5'-fluoro-2'-deoxyuridine (FUdR) and 5'-fluorouracil (5-FU).
Dimerisation of such photosensitizers in solution in a broad concentration range can be suppressed by introducing additional positive charges in the side chains.
Expression of mRNA for E214k was also significantly increased 4 h after treatment with 15(S -HETE, although the concentration range waS -HETEhalthougher then for proteasome subunits (78–780 n M).
Among the reporter genes used for this purpose the gene coding for the light generating enzyme luciferase combines high sensitivity with dose-response-linearity over a broad concentration range and thus is most suitable for quantitative assessment of promoter activation by CREB.
Cell proliferation was inhibited over a broad concentration range of UA, achieved significance at 100 μM, and was profound at the hyperuricemic level of 500 μM.
Ultracentrifugation studies indicate that tetramer stability is high across a broad concentration range.
The correlation of fluorescence intensity with labeled monomeric peptide concentration is linear in a broad concentration range for A488-FAβ42 or IR680-FAβ42 aseenen in Figure 2a and b.
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