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While broad coexpression of these factors is suggestive of a rudimentary vertebrate-like chondrogenic program, amphioxus pharyngeal mesoderm does not express SoxE or SoxD, two factors essential for the formation of all vertebrate cartilages.
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However, the lack of broad coexpression of cartilage marker orthologs, including ColA, in amphioxus pharyngeal endoderm indicates this tissue does not deploy a vertebrate-type skeletogenic gene program at larval stages.
On the other hand, as described recently in amphioxus, there is not a broad coexpression of cartilage marker genes in this region of the embryo [ 25].
The coexpression of these four genes in a full related cluster gives support to the indication that all produce IFITM proteins.
The coexpression of these clusters suggests that they might be controlled by common factors and play roles together.
Here, the coexpression of these two proteins in COS-7 cells allowed us to confirm that they colocalized in early and recycling endosomes.
Coexpression of these proteases resulted in 95% TUNEL positivity.
Overexpression of RASSF1A or Nore1A inhibits MST1 activation, but coexpression of these RASSF proteins with Ras enhanced MST1 activity [16].
Under physiological conditions, the coexpression of these proteins does not occur, since they typically induce opposite effects [ 6].
Moreover, the mutual rank for coexpression of these two genes is the highest in their respective gene networks.
These data clearly demonstrate the groups of peaks that are highly positively correlated, indicating coexpression of these peaks in individual tumors.
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