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As already stated for PCBs and PFCs, however, herring gulls are exposed to a broad cocktail of contaminants, and additive/synergistic effects must be taken into account, e.g., as observed for PCBs and PBDEs [100].
It must also be noted that vaccines aimed at eliciting the alloimmune response to a broad cocktail of HLA alleles present in a regional population could significantly compromise prospects for organ and tissue transplant among vaccinated individuals.
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In addition, the use of a broad acting cocktail of protease inhibitors at high concentration had little effect on the IgG fragment pattern for MAb 2G12.
First, cells were scraped in PBS, and after centrifugation, the cell pellet was reconstituted in a hypotonic lysis buffer [10 mmol/l HEPES (pH 7.9), 10 mmol/l KCl, 0.1 mmol/l EDTA] supplemented with 1 mmol/l DTT and a broad-spectrum cocktail of protease inhibitors (Sigma-Aldrich).
Therefore we administered a cocktail of broad spectrum antibiotics to WT animals for four weeks [7].
Notably, effects of metformin in improving glucose homoeostasis in high-fat mice are abolished through a cocktail of broad-spectrum antibiotics [ 149].
Hazen's group further demonstrated that a cocktail of broad-spectrum antibiotics could suppress intestinal flora in mice and prevent production of atherogenic TMAO from the choline in ingested egg yolk lecithin.
Indeed fibrosarcoma and melanoma cells, in the presence of a cocktail of a broad spectrum protease inhibitors, convert their motility style from proteolytic to amoeboid, thus undergoing MAT.
Because of TB's extreme resistance, patients must now take a cocktail of harsh, broad-spectrum drugs for months.
Passive immunization based on mAbs, however, may require a cocktail of mAbs with broader specificity to provide full protection, since mAbs are generally specific for single epitopes.
However, passive immunization based on mAbs may require a cocktail of mAbs with broader specificity in order to provide full protection since mAbs are generally specific for single epitopes.
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