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The CA-RMSD of the specificity determining segment Val pTyr+1 -Pro pTyr+2 -Met pTyr+3) goes from 4.0±1 Å at 3000K, to 3±1 Å with a cooling rate of 50 ps/step, to 2±1 Å at 500 ps/step; 94% of the population lie in a broad cluster with an average CA-RMSD of 2±1 Å, and 28% of the population in a tight sub-cluster with a CA-RMSD of 0.6±0.1 Å (Figure 2D F and 3D F).
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In the case of pYVNV, 50% of the population is in the β-turn conformation, 25% of the population forms a slightly broader cluster with a CA-RMSD of 2 Å from the extended conformation, and another 12% lie in a cluster about 6 Å from both the extended and the β-turn conformation, corresponding to a conformation in which the peptide forms a roughly 90° bend towards the CD loop.
There was also another very broad cluster of feline coronavirus with feline panleukopenia virus and other enteropathogenic species (N = 177, Figure 4[C]) with F CoPaCl and F CoPa representing 37% of that cluster, though these profiles were not observed more or less than expected (P > 0.091, Figure 5).
A broad cluster was deemed as one with a dominant peak if the TSS with the highest frequency of tag counts constituted at least 50%% of the total tag count.
Kidd et al used 128 AIMs to characterize samples from 119 populations into 8 broad clusters, which agree with continental boundaries.
RNA polymerase II-dependant promoters of vertebrates have previously been divided into two groups, categorised as either TATA or CpG types, the former with a tight TSS a strict distance from the TATA box and the latter with broad clusters of TSS [ 62, 66].
Several broad clusters of traits were identified, which each correlated with a number of context-specific behavioural traits.
Cow parsnips are perennials, often several feet high, with large compound leaves and broad clusters of white or purplish flowers.
We found three broad clusters when performing a PCA plot.
Two broad clusters of views emerged from the interviews.
Broad clusters were further categorized based on their peakedness.
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