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These results indicate that metabolism-based strategies may offer new therapeutic opportunities with broad clinical implications.
The studies presented here therefore have broad clinical implications and suggest a role for E2 in the modulation of immune responses during an endotoxin challenge.
This has broad clinical implications for delivering therapeutic HPV DNA vaccines.
In conclusion, we were able to delineate a novel c-Rel-, NFATc2- and COX-2-dependent antiapoptotic signalling pathway in PDAC with broad clinical implications for pharmaceutical intervention strategies.
The elucidation of the molecular mechanism of TKI resistance has broad clinical implications such as the early identification of resistant cases, personalized modulation of drug regimens and facilitating the screening of new targets for therapeutic intervention.
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Our findings indicate the neural mechanisms underpinning interindividual susceptibility to psychological symptoms associated with inflammation-induced sickness and have broader clinical implications across medical specialties in which these common symptomatologies might be targeted at the level of the central nervous system.
More importantly, the results have broad research and clinical implications.
In this sense, our work may have broad physiological and clinical implications.
The increasing prevalence of carbapenem resistance has broad and significant clinical implications because mortality and the cost of care are significantly increased in patients with carbapenem-resistant infections.
However, comparing this method as a gold standard to the usual methods of medications documentation was a crucial objective of this study and thus has broader clinical research implications.
On the contrary, stereotactic intracerebral cell delivery is likely to offer a broader therapeutic time window, although clinical implications are limited due to invasive surgical procedures.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com