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Tethering is generally carried out by two broad classes of molecules: extended, coiled-coil proteins such as the so-called Golgin proteins, or multi-subunit complexes such as the Exocyst, COG or Dsl complexes.
Straightforward chemical properties such as charge and number of unpaired electrons are used to define broad classes of molecules such as ion and radical.
Nevertheless, common themes have emerged that apply to broad classes of molecules, including dynamic phosphorylation of histones and nuclear factors.
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Tumour suppressor genes encode a broad class of molecules whose mutational attenuation contributes to malignant progression.
"The sample preparation method can be applied to a broad class of molecules," say Longchamp and friends.
Phytochemicals are a broad class of molecules with bioactive properties that are derived from botanical sources.
A very active target in the LPS/TLR4 pathway to which a broad class of molecules can bind or react and consequently inhibit the activation of TLR4 is MD-2, the co-receptor of TLR4.
These methods are ideally suited to study alkali dimers, but in order to access broader classes of molecules and a larger range of temperatures a different approach was necessary.
In weeds, herbicide resistance can arise from elevated CYP activity, which is particularly problematic because it can increase resistance to a broad class of related molecules [ 18].
Toll-like receptors (TLRs) are a family of immune defense proteins that appear to have evolved to detect molecules that are common to broad classes of pathogens, but are not present in our own cells.
Amino acid sequence and 3-dimensional analyses demonstrated these molecules to contain iterations of the conserved γ-core motif found in broad classes of classical antimicrobial peptides.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com