Sentence examples for broad changes in protein from inspiring English sources

In vitro cell culture has been used to examine differential gene expression of B. burgdorferi in response to altering pH and temperature; however the broad changes in protein abundances under different pH and temperature conditions have not been previously elucidated.

Estrogen exerts its biologic actions, including broad changes in gene expression, through nuclear proteins called estrogen receptors (ERs), which now include two subtypes [ 3]: ER-α and ER-β.

Using gene ontology analysis of DE genes to reduce complexity, there were broad changes in nucleotide binding, oxidoreduction and defence protein biosynthesis (Additional file 2: file S1); however, whilst used extensively in model species, gene ontology is less powerful in non-model crops as GO, KEGG or Panther terms were not available for many genes (<60 % annotation of unique transcripts).

Collectively we found that the loss of EC was accompanied with a strong downregulation in both RNA and protein levels of Tgfb1, and broad changes in ECM composition and structure in Tie2Cre and MesP1Cre Flk1 cKO mutants.

This study suggests that HER overexpression orchestrates broad changes in the tumor microenvironment by altering the secretion of a diverse variety of biologically active proteins.

Compatible host-virus interactions result in systemic infections that trigger broad changes in gene expression [ 49].

Such broad changes in gene expression involve the action of an array of regulators.

Such broad changes in gene expression likely involve coordinated actions of multiple pathways and regulators.

"There's been a broad change in the security environment".

But clearly broader changes in the culture accelerated the shift.

This macabre commerce takes place against broader changes in Americans' views of capital punishment.