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This again might suggest that cell-loss and/or changes in organ function/morphology are more important than broad changes in gene expression in the decrease in health that typically accompanies increasing age.
Such broad changes in gene expression likely involve coordinated actions of multiple pathways and regulators.
Such broad changes in gene expression involve the action of an array of regulators.
Compatible host-virus interactions result in systemic infections that trigger broad changes in gene expression [ 49].
In this lineage, specialization to the fish host was correlated with a massive gene inactivation and broad changes in gene expression.
Taken together, the results identified broad changes in gene expression between reproductive and non-reproductive states of high and low saccular activity, respectively.
Similar(47)
It also revealed broad changes in genes involved in small molecule metabolism, which remain to be deciphered.
The extent and kinetics of the ESR appear to be dependent on the severity of the stress, since cells exposed to increasing stress often display broader changes in gene expression.
Therefore, our proteomic analysis of the WAT revealed similarly broad changes in the gene expression spectrum in response to HFD intake.
21 In SRF-VP16 iHep mice, conditional activation of SRF-VP16 elicited broad changes in hepatocellular gene expression resulting in hyperproliferative nodules, followed by rapid progression to HCC.
In order to understand broad changes in functional categories of genes we performed a gene set enrichment analysis (Additional file 5).
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broad changes in training
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