Sentence examples for broad cellular functions from inspiring English sources

The highly diverse Numb-associated kinase (NAK) family has been linked to broad cellular functions including receptor-mediated endocytosis, Notch pathway modulation, osteoblast differentiation, and dendrite morphogenesis.

These results suggest SmpB and Hfq are involved in broad cellular functions, including growth rate regulation.

Together these findings illustrate the crucial role of the nuclear serine-threonine kinase ATM in signaling DSBs and in coordinating the complex network of broad cellular functions required to recover from radiation insult.

Finally, proteins with extended ANK repeat domains (e.g., TRP channels, elongation factors, protein kinases and phosphatases, and various scaffold proteins) may also interact with diverse partners via combinatorial uses of multiple, quasi-independent binding sites and thus are particularly suited as adaptors for assembling macromolecular complexes with broad cellular functions.

Additionally, we observed several terms that could be gathered into a growth and differentiation group (six terms), ion binding (two terms), broad cellular function (11 terms), and two terms that stand separately.

Our results suggest that network analyses can be a useful tool for helping to understand how the CTD regulates broader cellular functions.

Therefore changes in the expression patterns of protein families under different experimental conditions can provide clues about regulatory mechanisms, the relationships between broader cellular functions and biochemical pathways, as well as interactions between different protein motifs [ 2- 7].

Although this property may be a major contributor to the maintenance of lens clarity, the early changes in the alphaA/BKO lenses indicate a much broader cellular function for alpha-crystallin.

This adaptive response should involve a coordinated function of several genes and pathways, regulated by transcription factors with a broad cellular role.

Follow up genome scale studies have now to clarify how broad the cellular function of this novel posttranslational modification is in total, and how many other proteins are functionally regulated by histaminylation.

This established, they examined a broad range of cellular functions, eventually discovering the role that ion channels play in such diseases as diabetes, cystic fibrosis, epilepsy, several cardiovascular diseases, and certain neuromuscular disorders.