A discrepancy in cell specificity, between the full-length and pΔ(A25 -GFP construct wA25 -GFPved, the latter showing broader constructificity and revealed green fluorescent protein (GFP) activity in other neural cells in the mid and hindbrain area (Fig. 5).
In summary, we have reported the detailed expression pattern of a novel retinal marker with broad cell specificity, useful for retinal characterization in rodent experimental models.
Forebrain expression was observed, but with a broader cell specificity shown by lack of co-localization with the full-length zebrafish RFP construct, and GFP activity observed in midbrain and hindbrain neuronal cells.
Although these toxins have broad target cell specificity, M. haemolytica Lkt is specific for ruminant macrophages, neutrophils and all leukocyte subsets [ 37].
The broad tumor cell specificity of the synthesized disaccharide dye conjugates was validated by the similarity in their uptake profiles in spite of the variation in their uptake efficiency for the different cancer and matched normal cell lines studied.
MMP9 is associated with macrophages and peripheral blood mononuclear cells and has a broad substrate specificity and may contribute together with collagenases to the degradation of fibrillar collagens, basement membrane components, and stromal extracellular matrix molecules [ 26].
With broad substrate specificity and H2O2-producing capability, POx has much application potential in many areas.
Human carboxylesterase 1 (hCexhibitsbroadbroad substrate specificity and is involved in xenobiotic processing and endobiotic metabolism.
Furthermore, Streptomyces PLDs present advantages related to their broad substrate specificity and ease of enzyme preparation.
GDSL esterases and lipases are hydrolytic enzymes with multifunctional properties such as broad substrate specificity and regiospecificity.
