Our conversation begins with an excellent CRISPR primer before traversing some fascinating questions about gene-editing patent litigation around the world, licensing issues, and the broader array of regulatory issues generated by such emerging technologies.
Pharmaceuticals, pesticides, air pollutants, industrial chemicals, heavy metals, hormones, nutrition, and behavior can change gene expression through a broad array of gene regulatory mechanisms.
The Dashboard provides support for a broad array of research and regulatory programs across the worldwide community of toxicologists and environmental scientists.
Stem-cell research involves a broad array of societal stakeholders, including regulatory decisionmakers, translational researchers in academia, and private companies.
VEGF-C/VEGFR3 signaling in NSCs downregulates the expression of Bmi-1 and Rest, which interact with a broad array of transcriptional and epigenetic regulatory cofactors to maintain sternness and inhibit NSC differentiation (Abrajano et al., 2010; Fasano et al., 2009).
This data suggested a very different but complementary mechanism for cancer gene deregulation: these MMU DMRs might represent a broad array of tissue- or cell type-specific regulatory sites important for development and differentiation.
However, regulatory sequences represent a broad array of components including enhancers, repressors, silencers, and other boundary elements.
Calpains are regulatory proteases with a broad array of functions and are involved in cell mobility, cell cycle progression, and the regulation of clotting factors.
As we increasingly recognize the complexity of the pollutants in indoor and outdoor microenvironments, a broad array of inhaled mixtures has assumed scientific, public health, and regulatory importance.
MMP-2-dependent type 2 polarization may represent a key immune regulatory mechanism for protection against a broad array of disorders, such as inflammatory, infectious, and autoimmune diseases, which can be hijacked by tumors to evade immunity.
