Sentence examples for broad array of pathways from inspiring English sources

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In spite of the complex genetic architecture, these discoveries demonstrate that a broad array of pathways underlies the genetic heterogeneity of SSc, including innate immunity pathways (Toll-like receptor, interferon, DNA clearance during apoptosis), adaptive immunity pathways [interleukin (IL -12], and fIL -12] pandways.

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A wide array of pathways has been shown to affect these processes.

The differentially expressed genes conformed to a broad array of biological pathways and gene networks that were under- or over-represented in uremia compared to normal subjects.

This approach was based on the concept that we could sample a broad array of activation pathways and, thereby, develop a general profile of immune responsiveness rather than define the responsiveness of specific innate or adaptive immune pathways.

These observations, in combination with the broad array of metabolic pathways downstream of DHPS and folate biosynthesis, stimulated us to investigate the genes that influence the activity of sulfanilamides in plants.

Understanding the role of the PfRh and ebl proteins in alternate invasion pathways is critical to our ability to devise rational vaccine combinations that will provide immune responses that block a broad array of the pathways and ultimately may disrupt merozoite invasion.

The signaling genes rapidly up-regulated by E2 function in a broad array of signal transduction pathways.

In the human heart, which comprises a broad array of cell types, signaling pathways within myocytes and crosstalk between myocytes and nonmyocytes play crucial and interdependent roles in ensuring that the heart responds appropriately to physiological and pathological stimuli (Tian and Morrisey, 2012; Tirziu et al., 2010).

Although Scf elicited rapid responses in some intracellular pathways that we interrogated (Ras/MAPK, PI3K/AKT) in all of the HSC/HPC cellular subsets we analyzed, Thpo stimulation profiles were stronger in HSC/MPP (compared to GMP/CMP or MEP) and consisted of the activation of a broader array of intracellular pathways (Ras/MAPK, PI3K/AKT, JAK/STAT).

Inspired by breakthroughs in molecular and cellular biology, a number of novel synthesized chemical compounds and recombinant antibodies have been developed to selectively target oncogenic signaling pathways in a broad array of tumor types.

Notch signaling pathway regulates a broad array of cell fate decisions in various tissues and in all stages of development (embryonic to adult).

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