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Hypoxia is a potent stimulus known to induce changes in expression of a broad array of genes.
However, general effects on gene expression have not been well characterized, and the mechanisms by which mTOR signaling affects the expression of a broad array of genes are less well defined than is the case for its other biological effects.
Furthermore, while most research on the genetic basis of risk attitudes have focused directly on dopamine receptors and the dopamine and serotonin transporter genes, we find that genetic variation in a broad array of genes with ties to the regulation of dopamine and serotonin might be important for understanding individual risk attitudes.
It is apparent that this involves a broad array of genes beyond those just associated with environmental stress.
Overall, our annotation results suggest that our reference transcriptome (and corresponding SNPs) represent a broad array of genes covering a substantial proportion of the Douglas-fir transcriptome.
The study showed high levels of transcriptional activity and differential regulation of a broad array of genes beyond those associated with environmental stress during the dormancy period.
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Pharmaceuticals, pesticides, air pollutants, industrial chemicals, heavy metals, hormones, nutrition, and behavior can change gene expression through a broad array of gene regulatory mechanisms.
The powerful, modulatory control exerted by DA over both cognitive and motor behavior and the incomplete understanding of the determinants of risk for DA-associated brain disorders suggest that a broader array of genes exists that controls DA signaling.
STAT3 dimers, induced upon phosphorylation by members of the JAK tyrosine kinase family, enter the nucleus and activate a broad array of target genes.
In the mosquito Aedes aegypti, the wMelPop-CLA strain of Wolbachia significantly alters the miRNA profile of A. aegypti, thereby manipulating a broad array of host genes to facilitate self-maintenance [ 13, 16, 18– 20].
However, transcriptional profiling revealed that LXR SUMOylation site mutants were capable of mediating ligand-dependent repression of a broad array of inflammatory genes (e.g., those annotated with the 'Immune system process' GO term; Figure 2C).
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