Sentence examples for broad alterations from inspiring English sources

We defined broad alterations as those spanning >50% of a chromosome arm.

The nature of the alterations also differs, e.g. focal versus broad alterations.

It is reasonable to assume that the RA pathogenesis is influenced by broad alterations of gene expression in general.

Indeed, there have been no systematic attempts to understand the broad alterations in children's psychological well-being as they recover and return to normal activities post-PICU.

Functional annotation of the protein-coding mRNAs and isoforms indicated broad alterations in immune response, cell activation, metabolic processes, and RNA modification.

Discrepancies between the mRNA and protein expression for several jun/fos genes suggest broad alterations of post-transcriptional processes in the RA SM.

Second, the directions taken by technological trajectories and aggregate demand in advanced economies seem to point toward a broad alteration of the balance of locational advantages for production fragments, decreasing the weight of labor costs and augmenting the relevance of local availability of other complementary intangible assets.

However, their study does not provide a basis for recommending a broad alteration of blood lead screening strategies.

By pre-treating T98G cells with different dose of LPS, it was found that LPS treatment caused a broad alteration in gene expression profile, but did not cause obvious cell death.

The broad alteration of the metabolic profile observed in wild type worms upon prohibitin depletion, prompted us to examine its effect on the H NMR profile of daf-2 mutant animals.

Together these findings confirmed that MB tumors harbor abnormal levels of distinct NOTCH ligands, which likely results in a broad alteration of the fine-tuning regulation of the signaling pathway.