Sentence examples for broad activity in from inspiring English sources

The main effects of temporal irregularity, obtained through the contrast Temporal Irregular vs. Temporal Regular (for all submodalities), showed broad activity in the dorsolateral frontal cortex, corresponding to, but extending beyond, Brodmann Area 46 (p<0.001 uncorrected) into Brodmann areas 9, 45 and 44.

Vitespen failed to show broad activity in randomized clinical trials despite encouraging results in select patients.

In the field of antineoplastic chemotherapy, taxanes (paclitaxel and docetaxel) represent an important class of compounds, with broad activity in solid tumours (Rowinsky, 1997).

The evolutionary conservation of the hydrophobic pocket involved in dimerization together with PK9119's relatively broad activity in inhibiting both L. major and (to a lesser extent) D. rerio SAS-6 could suggest that PK9119 targets this pocket.

Benevolence International Foundation, an Illinois-based charity with broad activities in Bosnia, has emerged as a central focus of the investigation into the finances of Osama bin Laden and his Qaeda terrorist network.

Because indirect effects can arise from multiple direct chemical target interactions, chemicals logically show broader activity in these assays.

In subsequent mechanistic analysis reported here, we have now established that DUSP6 depletion has a broader activity in sensitising cells not only to EGFR inhibitors but also to additional targeted agents and to DNA-damaging agents.

In preclinical studies, CI-1040, a MEK inhibitor, has been investigated in a panel of human cancer cell lines and showed broad activity, particularly in cell lines harboring the BRAF mutation [ 76].

These compounds have also shown relatively broad activity against other viruses in vitro and in vivo in animal models (Dengue, Coronavirus OC43, SARS etc).

Metformin may have broad activity against carcinogenesis in general, making it a more attractive chemoprevention agent than disease site-specific compounds such as tamoxifen or raloxifene 17.

In addition, propolis has broad activities against P. multocida in vitro and in vivo (in the tracheal region of the rabbits) [ 31].