Sentence examples for broad activation of the from inspiring English sources

Epinephrine, a sympathomimetic drug, does not activate hBAT at a dose that leads to broad activation of the SNS (Cypess et al., 2012), suggesting that cold-exposure activates specific sympathetic pathways responsible for hBAT activation.

We show here, that following its natural route of infection, wild-type MV induces a strong and broad activation of the immune system, the generation of MV-specific humoral and cellular anti-viral responses, accompanied by an increase in the frequency of regulatory CD4+CD25+Foxp3+ T cells.

This analysis yielded broad activation of the AON, consistent with results by Cross et al. 25 from a similar analysis.

Loss of RPS19 induces broad activation of the p53 pathway and apoptosis in embryos, including of erythroid cells, which is consistent with observations from murine models.

The broad activation of the immune system and deregulation of an immunologic homoeostasis achieved by blocking CTLA-4 might be responsible for the development of inflammatory or autoimmune toxicities, reported in ∼15% of the patients (Robinson et al, 2004).

On the other hand, we observed a significant increase in the number of cells within the cambium at later time points for the 2101 022 MFR cultivar, both in organized and disorganized regions (Additional file 6: Figure S4C), which is indicative of a broad activation of cell division within the cambium, as has been previously described for a good-rooting reference cultivar [ 43].

However, the broad activation of transcription factors and pro-inflammatory genes suggests that other components of TGRL lipolysis products also could be playing a part in addition to fatty acids.

In the zebrafish blastula, the general delay in zygotic gene activity is followed by the sudden and broad activation of a large number of genes representing all main gene ontologies (Kane and Kimmel, 1993; Mathavan et al, 2005) leading to gastrulation.

In particular, the authors show that changing frequency of stimulation can change the brain response from broad activation of forebrain circuits for high frequency stimulation to decreased arousal and negative BOLD signals for low frequency stimulation.

At the late stage of infection, increased pathology and viral load in HR was accompanied by a broad activation of genes involved in adaptive immunity and particularly T cell responses, probably reflecting the increased infiltration and homing of virus-specific T cells to the infected heart.

Mechanical stimulation was performed with the fire polished tip of a bent glass rod mounted to the membrane of a loudspeaker in the cutaneous region known to elicit "pocket scratch" [12] which results in a broad activation of cells [59].