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Morphine-activated MOR enhances NMDAR-mediated glutamate responses [14], bringing about the activation of CaMKII [15].
In P. aeruginosa, a triggering mechanism of the T6SS has been proposed where a serine-threonine phosphorylation event has been considered to be essential in bringing about the activation of the T6SS system [3].
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Both activation and inhibition of the classical NF- κB pathway can bring about the permanent changes in human stem cells.
Our results begin to reveal the downstream interplay of the signaling events brought about by the activation of each of the two receptors, indicating the biological effect of receptor/ligand specificity.
However, it cannot be excluded that the hypotension observed in the case 1 and 4 was brought about by the activation of the vascular β2 receptors, which overcame the increased vascular resistance mediated by the action of romifidine administered in premedication on the α1 receptors.
Knowing that X and Y are associated amounts to knowing a causal fact: that activating Xs will bring about the activation of Ys and vice versa.
Progesterone brings about inhibition of adenylate cyclase and activation of the Mos/MEK1/p42 MAP kinase cascade, which ultimately brings about the activation of the universal M phase trigger Cdc2/cyclin B. Oocyte maturation provides an interesting example of how signaling cascades entrain the cell cycle clock to environmental changes.
The trauma and organ damage developing from the shock-induced hypoperfusion bring about the activation of the inflammatory cascade with subsequent vasoplegia [ 48, 49].
Among the STATs, only STAT3 and STAT5 can bring about the activation of cyclin D1 (Bromberg et al. 1999; Calo et al. 2003; Leslie et al. 2006).
In summary, NRII brings about the activation (phosphorylation) of NRI when it is not in a complex with PII and brings about the rapid inactivation (dephosphorylation) of NRI-P when it is in a complex with PII.
This mechanism brings about the activation of wild-type Raf monomers, is independent of Ras binding and of inhibitor-induced dimerization, and may potentially have more widespread consequences than the mechanisms relying on activated Ras [113].
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