The introduction of LFA-1 ligands on the particle surface overcame limitations brought about by TCR/CD3 contact stabilization requirements and helped to elucidate low TCR/CD3 surface engagement densities which did not support cell-particle contact stabilization.
This is, however, not unexpected, given SNP chip content and association power limitations brought about by the sample sizes employed (Table 1).
In 2005, after several years of tight budgets brought about by recession, the spending limitations of TABOR, and other budgetary obligations, the Colorado General Assembly referred Referendum C, a statewide "de-Brucing" measure, to Colorado voters.
The disability field is racked with the dilemma of how to manage the young people exhibiting what are euphemistically called "challenging behaviours" – violence and aggression brought about by the frustration of their physical limitations and of their inability to communicate.
The unnecessary increase of resolution at smaller radius typically brought about by polar coordinates, with its consequent stability limitations, is avoided by changing the number of azimuthal Fourier modes with the radial coordinate itself.
The inherent limitations of the two tests could bring about high positive result.
These projected benefits ranged from learning more about the origin and manifestations of their condition, to learning additional ways to cope with their symptoms and limitations, to easing the boredom and inactivity brought about by their imposed lifestyles.
The limitation of testing-personnel quality and testing technology could bring about hidden failures for ignorance of some defects in devices.
Due to funding limitations the duration of the intervention was less than desirable to bring about change [ 28].
In order to overcome these limitations, the Semantic Web, based on ontology, was introduced by W3C to bring about significant advancement in web searching.
Neither would be easy to bring about.
