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For technology companies, the cost of labor is minimal compared with the expense of buying parts and managing supply chains that bring together components and services from hundreds of companies.
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It makes phones for a number of brands, bringing together components and manufacturing from a variety of sources to build each one.
The da Vinci's 33,000-square-foot assembly plant, down the road from corporate headquarters, brings together components, many of them custom-made, from suppliers all over the world.
Since the 1990s, the Neo-Burlesque icon has been part of a new performance movement, bringing together components of striptease, dance, comedy and theatrical mayhem in one bombastic one-woman show.
Therefore, pseudokinases can be envisaged as 'elastic' scaffolds, bringing together components of a particular signalling network, as well as being allosteric activators of protein kinases.
Pseudokinases act as signal transducers by bringing together components of signalling networks, as well as allosteric activators of active protein kinases.
Filament formation could have a synergistic effect on the elongasome by bringing together components that reach a higher local concentration through the interaction with polymeric MreB.
Given that Rac is known to activate the WAVE complex (Derivery and Gautreau, 2010), our finding that Nhsl1b and Scrib physically and genetically interact raises the possibility that Scrib could function as a scaffold that brings together components that regulate assembly (via Nhsl1b) and activation (via Rac) of the WAVE complex in migrating FBM neurons.
The observation that many complex complexes tend to be composed of proteins with a shorter mean length may also be related to this phenomenon since the evolution of large complexes may depend on how often and easy it is to bring together undamaged components.
It is the task of the system integrator to bring together these individual components into a complete working system.
You narrow it down and bring together the key components you think are necessary for this, and then off you go with a big fat wallet, wads of cash and an endless credit card balance to the stores.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com