When expressed alone, however, DRAM1 can modulate autophagy but does not cause cell death, indicating that autophagy is required but is not sufficient to bring about this response (71, 72).
"And it has to bring about negative responses".
Genes activated in response to biotic stress and/or stimuli were also activated owing to the fact that both biotic and abiotic stress stimuli share a common signaling cascade to bring about physiological responses [ 55].
Autophagy is also highly adaptable and the rate and cargoes of autophagy can be altered to bring about desired cellular responses to intracellular and environmental cues, disease states and a spectrum of pharmaceutical drugs.
In the context of increasingly hectic lives, surveys that are perceived to take too long to complete may not be viewed favorably and may bring about diminished response.
On the other hand, they might also directly bring about inflammatory response of the target cells through corresponding receptors and up-regulate the production of PGE2 from inflammatory cells which will advance the inflammation and pain [ 40].
Because, let's face it, authors are professional "story tellers" who seek to bring about an emotional response.
The lower CRP in non-survivors, on the other hand, might indicate immune exhaustion or liver failure, with a failing attempt to bring about an effective response in order to establish control of their acute illness.
During the long bombing campaign named Rolling Thunder, President Lyndon Johnson personally chose targets in Indochina, believing that "carefully calculated doses of force could bring about desirable and predictable responses from Hanoi".
Under conditions of internal resonance these effects may bring about complex forms of response where the normal linear resonance of a directly excited mode is absorbed, and indirectly excited modes show simultaneous large non-synchronous responses.
