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This is a legitimate phrase in written English.
You can use it when you want to describe an event or situation that has the potential to trigger significant and far-reaching implications or effects. Example sentence: The recent economic recession has brought about profound changes in the theater industry.
Exact(2)
Many economists also argue that the growing dominance of finance, accelerated by the Big Bang, helped to bring about profound changes in the UK's economic model.
The appearance of such a cancer workhorse will bring about profound changes on the cancer landscape — not just for patients but for researchers and drug regulators as well.
Similar(58)
"A very simple clarification [of the amendment] on paper would bring about profound change, not just for women in Kenya, but for women around the world".
The Environmental Protection Agency, a federal body, also raised concerns about "potential risks" to the watershed.The path of demand in gas's new age is hard to predict, but abundant new sources could bring about profound change in patterns of energy consumption.
Hugh Hudson took on the Education portfolio, an important role in a government that was determined to bring about profound change to the South Australian education system.
What appeals to me about filmmaking is that it extends the conversation and has the power to inform and bring about profound change.
Rapid urbanization and spontaneous economic development has brought about profound changes in urban landscapes throughout the world.
The development of Guam into an important U.S. military base brought about profound changes in the island's agricultural patterns after World War II.
California's struggle with air quality, particularly in the Los Angeles Basin, brought about profound changes; in 1966, the state was the first to require smog equipment, and it wasn't long before the federal Clean Air Act clamped down.
Caribou require a great deal of space to survive, but the clearing of land for one development project after another, combined with the building of roads and other means of access for resource exploration, are bringing about profound changes to their habitat and making it easier for hunters to reach them.
The professionalisation of university curricula has brought about profound changes in the traditional academic education concept and faces the introduction of more professional courses into university systems.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com