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In this sense, robust sequences will tend to have low (strongly negative) values of D. By contrast, sequences under strong structural constraints will tend to have increased variance, as even single nucleotide mutations may bring about notable changes in the structural profile, and their robustness will therefore be decreased.
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We share a common understanding that the capacity and extent of human impact on earth ecosystems have changed profoundly, human induced climate change has already brought about notable adverse repercussions on society and economic development.
The participants recognized that the capacity and extent of human impact on Earth's ecosystems have changed profoundly, and realized that human-induced climate change has already brought about notable adverse repercussions that impact society and economic development.
With the start of the winter sports season fast approaching, the CIF Southern Section office released its 2016-2017 playoff groupings for boys' and girls' basketball and soccer and girls' water polo, which brought about several notable changes.
Furthermore, although there have been some notable successes in using artificial molecular machines to bring about property changes, few have been shown to perform useful tasks that cannot be accomplished by conventional chemical means.
"Then we will bring about big changes".
"But it does bring about some changes.
Little changes in SCMO and SCC ingredients bring about major changes in their workability and segregation.
Some of the programs are excellent and are useful for bringing about a change in culture but cannot bring about substantial changes in the sex ratio anytime soon.
Effectively altered preferences, in principle, should bring about positive changes in health service uptake.
There is also need to bring about academic changes in quality of teaching and evaluation system.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com