Briefly, we excluded SNPs based on low minor allele frequency (MAF <1%), low imputation quality, low call rate and deviation from the Hardy-Weinberg equilibrium.
Briefly, we excluded patients with documented contraindications for anticoagulation treatment, as well as those who received comfort measures only or were transferred out to other hospitals.
Briefly, we excluded women with unknown, inconsistent, or out-of-range reports for height, weight in 1976 or at age 18, age at menarche or menopause or each pregnancy, parity, and duration or type of postmenopausal hormone (PMH) use (n = 42,886).
Briefly, SNPs were excluded from the data analysis if the minor allele frequency was less than 1% and the call rate was less than 87% in the controls in each of the three study centres.
Briefly, SNPs were excluded if they were monomorphic or had a call rate < 96%.
Briefly, SNPs were excluded based on deviation from Hardy Weinberg equilibrium (p < 5.7 × 10−7) or if the study-wise missing data proportion was >0.05.
Briefly, subjects were excluded if they had any significant neurological disease other than incipient Alzheimer's disease, any history of significant brain lesions or head trauma, or psychoactive medication use (including antidepressants, neuroleptics, chronic anxiolytics or sedative hypnotics, etc).
Briefly, elements were excluded from the source apportionment modeling if > 90% of the samples had values below the MDL unless they were important tracer elements for potential source types.
Briefly, patients were excluded if they were not expected to remain in the ICU for 24 h or to survive 72 h; anuric; receiving renal replacement therapy, or had obvious haematuria, rhabdomyolysis or polycythemia.
